About The Lyme Disease Vaccine Study

Lyme disease is a common illness caused by a bacteria found in ticks. Bites from infected ticks can transfer the bacteria to humans and cause rashes, fever, and fatigue. Children account for a large portion of those at the greatest risk of Lyme disease. If left untreated, Lyme disease can progress to cause severe, sometimes permanent symptoms. Currently, there are no approved vaccines available to prevent Lyme disease.

VALOR is an ongoing clinical trial which has already enrolled more than 4,000 adults and 300 children. This study is evaluating if an investigational Lyme vaccine is safe and effective for preventing Lyme disease in people who have been exposed through tick bites.

Joining a clinical trial is an important decision. We hope it is one your family will consider.

Who Can Participate

Healthy children 5 years of age or older who live in or often visit outdoor areas that may expose them to ticks may be eligible to participate. Study participants cannot have been diagnosed with Lyme Disease within 3 months of enrollment.

Activities that may increase the risk of Lyme Disease include:

Live in or frequently visit areas where ticks that carry Lyme disease are found, such as wooded areas, tree lines, open fields, lakesides or riversides

Hiking, camping, fishing, hunting, or gardening

Owning a pet that has returned with ticks attached after being outside

Note: There are other requirements to participate in this study. A study team member will help determine if this study is a good fit for your child.

What To Expect

Your child will be randomly assigned to receive the study vaccine or a placebo (shot with no active ingredient). Neither you, your child nor the study doctor will know which has been assigned

This study will last about 30 months (2 and a half years). During this time, your child will have at least 7 in-clinic study visits, including 4-5 visits with blood draws. Additional blood samples may be needed if your child develops symptoms of Lyme disease.

Over the course of the study, you will need to report any changes in your child's health to the study team

The study vaccine and study-related procedures will be provided at no cost. Your child does not need health insurance to take part in this study.

Research studies are voluntary, and taking part in a research study is a personal choice. Your child may leave the study at any time, for any reason.

Before You Continue...

A first step as you consider this study is to answer a 5-minute online questionnaire about your child's health and medical history. If your answers show the study might be a good fit for your child, you may choose to be referred to a study clinic that you select. You will then be asked to provide your contact information for a study representative to contact you and discuss the next steps. Only the study staff can determine if you meet the study's eligibility criteria and are able to enroll in the study.

Click 'Next' to begin the questionnaire.

Question 1 of 3

A parent or guardian should answer the following questions.

Is your child or teen 5-17 years old?

Question 2 of 3

Does your child have any medical conditions or receive medical treatments and/or medications that suppress the immune system?

Question 3 of 3

Has your child been diagnosed with or treated for Lyme disease in the past 3 months?

Thank you so much for your interest in our Lyme Disease vaccine study and for answering our questions.

There may be other Pfizer research studies enrolling in your area in the future. If you would like to be notified about future research opportunities, we will collect your name,phone number, and email address so that a study representative may contact you about other research studies. Your contact information will not be used for any other purposes.

The individual responses you've provided will be used by Pfizer, or our partners supporting this study, to look for areas of improvement such as revising the criteria for participation in this study. Pfizer study team members and our partners will have access to reports containing aggregated data that will not be directly linked back to you. All information is stored on servers in the United States.

So far - So good!

Your child appears to meet the basic requirements for this Lyme disease vaccine study. However, only the research study staff can fully determine if he or she qualifies to enroll. Please enter your contact information and select "Find a Site" to see if there is a study site enrolling in your area. By submitting this form, you confirm that you are at least 18 years of age (or the legal age of consent in your state if it over 18) and that Pfizer or our partners may contact you about information related to research studies enrolling in your area.

Choose a Location

Please select a research site near you. This list displays sites located up to 50 miles away from the entered address. If you don't see a site near you, then select "The sites listed here are not convenient for me." Study locations are being added regularly. A study representative will call you if a research site becomes available in your area.

The sites listed here are not convenient for me.

Sorry, your child is not eligible to participate in this study.

Thank you for your interest in this Lyme disease vaccine study and for answering our questions. Please consider entering your information below to be contacted about future clinical research opportunities. By submitting this form, you confirm that you are at least 18 years of age (or the legal age of consent in your state if it over 18) and that Pfizer or our partners may contact you about information related to research studies enrolling in your area. Contact your child's healthcare provider if you have any questions about their health.